INSIGHTS INTO TARGETING LKB1 IN TUMORIGENESIS

Insights into targeting LKB1 in tumorigenesis

Genetic alterations to serine-threonine kinase 11 (STK11) have been implicated in Peutz-Jeghers syndrome and tumorigenesis.Further exploration of the context-specific roles of liver kinase B1 (LKB1; encoded by STK11) observed that it regulates AMP-activated protein kinase (AMPK) and AMPK-related kinases.Given that both migration and proliferation a

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Detection of Cytotoxic Activity of Lectin on Human Colon Adenocarcinoma (Sw480) and Epithelial Cervical Carcinoma (C33-A)

Lectins comprise a Erasers heterogeneous class of proteins that recognize the carbohydrate moieties of glycoconjugates with high specificity.Numerous studies have shown that lectins are capable of recognizing specific carbohydrate moieties displayed by malignant cells or tissues.The present work was performed to investigate the effects of tepary be

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